McIndoe Memorial Research Unit and the world’s first specialist Burns Centre completed.
Key investigations into the immunological role of the thymus gland.
The National Eye Bank of preserved corneal grafts established at the Centre Microvascular anastomosis (joining of tiny blood vessels) pioneered in the UK.
The path of reconstructive surgery is radically changed by the success of the first great toe-to- hand transfer for a missing thumb.
The use of microvascular anastomosis surgery to successfully re-attach a finger to the hand of a two-year old, restoring the patient’s blood supply.
Pioneering the use of infra-red cameras to assess the depth of burns.
The first hand re-attachment operation successfully completed.
A breakthrough in using a tissue matching graft (employing cadaver donor grafts) significantly improves the success of a corneal graft for recipients otherwise known to have a high risk of graft failure.
Pioneering breakthrough in immunology of organ transplantation and tissue typing. Blond McIndoe at the forefront of tissue typing and the matching of grafts to their recipients. The work of the Centre contributes to the first heart transplant.
A unique Freeze Dry Skin Bank is set-up at Blond McIndoe leading to the mass collection of freeze-dried skin.
Important identification of another antigen, closely linked to Multiple Sclerosis. Studies into the possible mechanism of the disease followed the discovery.
Introduction of tissue typing into corneal grafting leads to the successful restoration of vision for many patients.
Further progress in successfully re-attaching limbs – hands from the wrist, and arms – is reported.
Important work undertaken in improving our understanding of graft rejection and how this impacts on the use of donated skin grafts.
Use of growth factors for reinnervation of peripheral organs developed.
The culturing of Schwann cells for transplanation to encourage nerve regeneration pioneered.
The first example, worldwide, of cultured skin cells used in combination with a new artificial skin, known as Integra, is published.
Pioneering nerve gap regeneration using synthetic conduits.
Pioneering the use of cultured skin cells for non-healing wounds for mastoid cavities of the ear.
The world’s first knee operation using cultured cartilage cells with grafts of cartilage pioneered and performed.
Cultured corneal epithelial cells grafted onto patients with damaged cornea restoring their sight.
Clinical study into the use of sprayed cultured keratnocytes on patients suffering from large full thickness burns established.
GMP suite built and accredited allowing the Blond McIndoe Research Foundation to culture a variety of cells for clinical use.
First use of DNA fingerprinting to study the fate of transplanted cultured cells on the surface of patients cornea completed.
Study into children’s scalds begins which makes use of cultured keratinocytes from the Centre.
The evaluation of novel technologies for improving wound repair continues with particular emphasis on skin and burns.